CNBC.com's MacKenzie Sigalos brings you the day's top business news headlines. A second wave of coronavirus infection overtakes Europe as the United States mourns 200,000 Covid-19 deaths ? the most of any country in the world. The 'After Hours' team asks public health experts and epidemiologists what notes Americans should be taking as Europe tries to tamp down on infection, and flu season approaches.

0:43 -- Dow, S&P 500 post 4 straight weeks of losses
1:03 -- Why Wall Street is leading the charge back to bring employees back into the office
4:10 -- CNBC Soundcheck
7:51 -- Europe's second wave of Covid-19
12:03 - Numbers Round

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